GPU and SATA connector clearance issue

Convert PCIe x1 slot to open ended Is there a safe way to cut the gpu blocking pcie slot Say for instance I decide to put a triple slot height graphics card in my 2012 Mac Pro, the second 16x slot would be blocked gpu stuck in slot CPU Cooler blocking PCIe port

gpu slot size My XFX AMD Radeon RX 580 GTS XXX Edition 8GB GDDR5 doesn't block one PCIe slot This is my configuration: GPU, Innateck USB ; NVME, SATA card