ABP688 人源mGluR5 拮抗剂

ABP688 人源mGluR5 拮抗剂 abp688 Results ABP688 BPND was significantly higher in men compared to women in the prefrontal cortex , striatum , and abp688 ABP688 is a high affinity human mGluR5 antagonist with anKi of nM Radioisotope-labeled ABP688 can be used as a PET tracer for clinical imaging of the mGlu5

abp688 ABP688 Rat No change of mGluR5 Kosten et al availability ABP688 Alcohol use disorder Human Altered mGluR5 signaling Akkus et al in the

abp688 ABP688 was originally shown to be a potent antagonist of quisqualate-induced phosphoinositol accumulation in L cells expressing recombinant human In vivo ketamine-induced changes in ABP688 binding to metabotropic glutamate receptor subtype 5 Biol Psychi- atry 77:266–275 Denys D, Mantione M,